A diet-wide association study for liver cancer risk: findings from a prospective cohort study in Chinese women.

ABSTRACT: Although dietary factors have been examined as potential risk factors for liver cancer, the evidence is still inconclusive. Using a diet-wide association analysis, our research evaluated the associations of 126 foods and nutrients on the risk of liver cancer in a Chinese population. We obtained the diet consumption of 72,680 women in the Shanghai Women's Health Study using baseline dietary questionnaires. The association between each food and nutrient and liver cancer risk was quantified by Cox regression model. A false discovery rate of 0.05 was used to determine the foods and nutrients which need to be verified. Totally 256 incident liver cancer cases were identified in 1,267,391 person-years during the follow-up duration. At the statistical significance level (P ≤ 0.05), higher i

SUBMITTER: Tuo JY 

PROVIDER: S-EPMC11658938 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature