Nomogram for predicting post-progression-free survival in patients with recurrent pancreatic ductal adenocarcinoma after radical surgery: a retrospective analysis.

ABSTRACT:

Background

Radical resection is the only curative method for patients with pancreatic adenocarcinoma (PDAC). However, nearly 85% of PDAC patients suffer from local or distant recurrence within 5 years after curative resection. The progression of recurrent lesions accelerates the mortality rate in PDAC patients. However, the influence of clinicopathological factors on post-progression-free survival (PPFS), defined as the period from tumor recurrence to the timing of the progression of recurrent lesions, has rarely been discussed. The present study aimed to explore the independent prognostic factors for PPFS and construct a nomogram for PPFS prediction.

Materials and methods

The 200 recurrent PDAC patients were divided into training and validation groups by leave-one-out cross

SUBMITTER: Qin D 

PROVIDER: S-EPMC11659012 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature