Maternal pesticide exposure and risk of birth defects: a population-based cross-sectional study in China.

ABSTRACT:

Objective

This study aimed to examine the association between maternal pesticide exposure during the periconceptional period and birth defects in their offspring.

Methods

A survey was conducted among 29,204 women with infants born between 2010 and 2013 in Shaanxi Province, Northwest China. All cases of birth defects were diagnosed using the International Classification of Diseases, Tenth Revision (ICD-10). Given the multistage sampling design, the generalized estimating equation (GEE) binomial regression models with log link and exchangeable correlation structures were used to analyze the association between maternal pesticide exposures and birth defects.

Results

Among the 29,204 subjects, 562 mothers had children with birth defects, resulting in an incidence rate of

SUBMITTER: Liu F 

PROVIDER: S-EPMC11659231 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature