Efficacy of <i>Curcuma longa</i> in relieving pain symptoms of knee osteoarthritis patients: a systematic review and meta-analysis of clinical trials.

ABSTRACT:

Objective

Osteoarthritis (OA), particularly knee OA, affects 24% of adults and is a significant cause of disability. Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used but have many adverse effects. Antioxidant and anti-iflammatory properties of Curcuma longa might decrease pain thus improving joint function.

Methods

This systematic review and meta-analysis evaluated randomized controlled trials (RCTs) on Curcuma longa efficacy for knee OA. We reported mean differences (MD) with 95% confidence interval (CI) for continuous outcomes and evaluated Visual Analog Scale (VAS) for pain and the Western Ontario and McMaster Universities Arthritis Index (WOMAC) total score over 4 to 6 weeks for treatment effects.

Results

Ten RCTs with 786 patients wer

SUBMITTER: Hidayat R 

PROVIDER: S-EPMC11659657 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature