Complete genome sequence of a novel extrachromosomal virus-like element identified in planarian Girardia tigrina.

ABSTRACT:

Background

Freshwater planarians are widely used as models for investigation of pattern formation and studies on genetic variation in populations. Despite extensive information on the biology and genetics of planaria, the occurrence and distribution of viruses in these animals remains an unexplored area of research.

Results

Using a combination of Suppression Subtractive Hybridization (SSH) and Mirror Orientation Selection (MOS), we compared the genomes of two strains of freshwater planarian, Girardia tigrina. The novel extrachromosomal DNA-containing virus-like element denoted PEVE (Planarian Extrachromosomal Virus-like Element) was identified in one planarian strain. The PEVE genome (about 7.5 kb) consists of two unique regions (Ul and Us) flanked by inverted repeats. Seque

SUBMITTER: Rebrikov DV 

PROVIDER: S-EPMC116598 | biostudies-literature | 2002 Jun

REPOSITORIES: biostudies-literature