Association between PaCO₂ and outcomes in patients who underwent extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest.

ABSTRACT:

Aim

The optimal arterial partial pressure of carbon dioxide (PaCO₂) for patients undergoing extracorporeal cardiopulmonary resuscitation (ECPR) remains unknown. We aimed to investigate the association between post-resuscitation PaCO₂ and neurological outcomes.

Methods

This retrospective cohort study analyzed data from the Study of Advanced Life Support for Ventricular Fibrillation with Extracorporeal Circulation in Japan, a multicenter registry study across 36 hospitals in Japan, including patients with out-of-hospital cardiac arrest (OHCA) admitted to intensive care units (ICU) after ECPR between 2013 and 2018. Good PaCO₂ management status was defined as a PaCO₂ value of 35-45 mmHg. We classified patients into four groups (poor-po

SUBMITTER: Kawakami A 

PROVIDER: S-EPMC11659811 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature