Optimal Stopping Ages for Colorectal Cancer Screening.

ABSTRACT:

Importance

Prior studies have shown that the benefits, harms, and costs of colorectal cancer (CRC) screening at older ages are associated with a patient's sex, health, and screening history. However, these studies were hypothetical exercises and not directly informed by data on CRC risk.

Objective

To identify the optimal stopping ages for CRC screening by sex, comorbidity, and screening history from a cost-effectiveness perspective.

Design, setting, and participants

This economic evaluation first validated the MISCAN-Colon (Microsimulation Screening Analysis-Colon) model against community-based CRC incidence and mortality rates for 2 subcohorts of the PRECISE (Optimizing Colorectal Cancer Screening Precision and Outcomes in Community-Based Populations) cohort. Subsequ

SUBMITTER: Harlass M 

PROVIDER: S-EPMC11659906 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature