Pan-Cancer Analysis of Postdiagnosis Exercise and Mortality.

ABSTRACT:

Purpose

The impact of postdiagnosis exercise on cause-specific mortality in cancer survivors and whether this differs on the basis of cancer site is unclear.

Methods

We performed an analysis of 11,480 patients with cancer enrolled in the Prostate, Lung, Colorectal, and Ovarian cancer screening trial. Patients with a confirmed diagnosis of cancer completing a standardized survey quantifying exercise after diagnosis were included. The primary outcome was all-cause mortality (ACM); secondary end points were cancer mortality and mortality from other causes. Cox models were used to estimate the cause-specific hazard ratios (HRs) for ACM, cancer, and noncancer mortality as a function of meeting exercise guidelines versus not meeting guidelines with adjustment for important clinica

SUBMITTER: Lavery JA 

PROVIDER: S-EPMC11659968 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature