Neutrophil-To-Lymphocyte Ratio as a Prognostic Indicator in Thyroid Cancer.

ABSTRACT:

Objective

In this study, we aimed to perform a comprehensive analysis to assess the prognostic value of neutrophil-to-lymphocyte ratio (NLR) levels in patients diagnosed with thyroid cancer.

Methods

We systematically searched multiple databases, including PubMed, the Cochrane Library, EMBASE, and Google Scholar, up until March 30, 2023, to identify relevant articles. The clinical outcomes evaluated in this study included overall survival (OS), progression-free survival (PFS), disease-free survival (DFS), and cause-specific survival (CSS).

Results

This analysis includes 21 articles with 5187 patients in total. The pooled results revealed that patients with high NLR levels had significantly poorer OS (HR: 2.578, 95% CI: 2.050-3.242, P < 0.001), PFS (HR: 2.143, 95

SUBMITTER: Gao Q 

PROVIDER: S-EPMC11660077 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature