Cost-effective identification of Barrett's esophagus in the community: A first step towards screening.

ABSTRACT:

Background and aim

The first step towards developing a screening strategy for Barrett's esophagus (BE) is the identification of individuals in the community. Currently available tools include endoscopy, less-invasive non-endoscopic devices, and non-invasive risk stratification models. We evaluated the cost of potential strategies for identification of BE as a first step towards screening.

Methods

Two hypothetical cohorts of the general population aged ≥ 50 years with BE prevalence rates of 1.9% and 6.8% were modeled. Four potential screening tools were evaluated: (i) risk stratification based on non-weighted clinical factors according to US/European guidelines, (ii) weighted risk stratification using algorithmic models, (iii) less-invasive devices such as Cytosponge + trefoi

SUBMITTER: Aoki T 

PROVIDER: S-EPMC11660199 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature