Synthesis, structures and Hirshfeld surface analyses of 2-hy-droxy-<i>N</i>'-methyl-acetohydrazide and 2-hy-droxy-<i>N</i>-methyl-acetohydrazide.

ABSTRACT: The structures of the title compounds 2-hy-droxy-N'-methyl-acetohydrazide, 1, and 2-hy-droxy-N-methyl-acetohydrazide, 2, both C₃H₈N₂O₂, as regioisomers differ in the position of the methyl group relative to the N atoms in 2-hy-droxy-acetohydrazide. In the structure of 1, the 2-hy-droxy-acetohydrazide core [OH-C-C(=O)-NH-NH] is almost planar and the methyl group is rotated relative to this plane. As opposed to 1, in the structure of 2 all non-hydrogen atoms lie in the same plane. The hydroxyl and carbonyl groups in structures 1 and 2 are in trans and cis positions, respectively. The methyl amino group and carbonyl group are in the cis position relative to the C-N b

SUBMITTER: Vashchenko OV 

PROVIDER: S-EPMC11660486 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature