A cross-sectional study of the association between depression and serum prostate-specific antigen (PSA) among U.S. males: national health and nutrition examination survey (NHANES), 2005-2010.

ABSTRACT:

Background

The association between depression and serum total prostate-specific antigen (PSA) concentrations remains unclear. To explore whether there is a relationship between depression and PSA in American males without prostate cancer (PCa), according to the National Health and Nutrition Examination Survey (NHANES) database.

Methods

Three biennial cycles of survey data from 2005 to 2010 were used in our study. Multivariate adjusted regression analysis, stratified analysis, trend testing, smooth curve fitting and multiple imputation (MI) were our main research methods. Depression was assessed by the Patient Health Questionnaire-9 (PHQ-9).

Results

The study included a total of 4185 participants. After adjusting all covariates, whether depression was used as a continu

SUBMITTER: Huang Y 

PROVIDER: S-EPMC11660593 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature