Hemolytic disease of the fetus and newborn and Rhesus alloimmunization in Latin American countries: a scoping review.

ABSTRACT:

Background

Hemolytic disease of the fetus and newborn (HDFN) is a condition due to maternal blood group antibodies targeting antigens in fetal red blood cells, with significant prenatal/perinatal morbidity and mortality. Severe HDFN cases are often associated with alloimmunization against Rhesus D (RhD) or Kell antigens. Information about HDFN epidemiology and treatment in Latin American countries is limited. This review aims to identify and synthesize the available evidence on the epidemiology and management of HDFN in this region.

Methods

In July 2023, EMBASE, PubMed, LILACS, and other databases were searched for articles reporting epidemiology, treatment, prenatal and perinatal outcomes, and patient journey of HDFN cases in Latin American countries. A snowball search of c

SUBMITTER: Junior MDC 

PROVIDER: S-EPMC11660609 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature