Serum creatinine to cystatin C ratio in relation to heart failure with preserved ejection fraction.

ABSTRACT:

Background

Sarcopenia was recognized to be one of the common comorbidities in heart failure (HF). The sarcopenia index (SI), based on serum creatinine to cystatin C ratio, was developed as a simple tool to evaluate skeletal muscle mass but has not been well-studied in the correlation of left ventricular ejection fraction (LVEF). The aim of this study is to analyze the SI in patients with HF, especially patients with HF with preserved ejection fraction (HFpEF), and to develop a prediction model for HFpEF.

Methods

The training cohort included 229 hospitalized patients with HF and 73 healthy controls (HCs) from the Third Affiliated Hospital of Soochow University between December 2019 and February 2022. An additional 78 patients with HF hospitalized at the same hospital between

SUBMITTER: Wang R 

PROVIDER: S-EPMC11660665 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature