Association between hemoglobin and in-hospital mortality in critically ill patients with sepsis: evidence from two large databases.

ABSTRACT:

Background

The relationship between baseline hemoglobin levels and in-hospital mortality in septic patients remains unclear. This study aimed to clarify this association in critically ill patients with sepsis.

Methods

Patients with sepsis were retrospectively identified from the Medical Information Mart for Intensive Care-IV (MIMIC-IV 2.2) and eICU Collaborative Research Database (eICU-CRD). Multivariate logistic regression analysis and restricted cubic spline regression were used to investigate the association between hemoglobin and the risk of in-hospital mortality. Additionally, a two-part linear regression model was used to determine threshold effects. Stratified analyses were also performed.

Results

A total of 21,946 patients from MIMIC-IV and 15,495 patients fro

SUBMITTER: Sheng S 

PROVIDER: S-EPMC11660889 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature