Infections Following Kidney Transplantation After Exposure to Immunosuppression for Treatment of Glomerulonephritis.

ABSTRACT:

Rationale & objective

Kidney transplant patients with glomerulonephritis (GN) as their native disease commonly have received pretransplant immunosuppression (PTI). This may contribute to the immunosuppression burden potentially increasing the risk for infections after transplantation.

Study design

Single-center, retrospective cohort study.

Setting & participants

Recipients of a kidney transplant from January 2005 until May 2020 at a tertiary care university teaching hospital.

Exposure

Patients with GN as their native kidney disease who received PTI for treatment of GN (n=184) were compared with nondiabetic recipients of kidney transplants who did not receive PTI (n = 579).

Outcome

First occurrence after transplantation of an infection outcome, either vir

SUBMITTER: Massicotte-Azarniouch D 

PROVIDER: S-EPMC11660976 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature