Loss to analysis in randomized controlled trials in CKD.

ABSTRACT:

Background

Nephrology has a limited number of randomized controlled trials (RCTs). The quality of randomized trials is compromised further when not all participants randomly assigned are accounted for transparently.

Objectives

Systematically evaluate RCTs in individuals with chronic kidney disease regarding reporting and accounting of data missing in outcome analysis.

Study design

De novo empirical evaluation.

Setting & population

English-language parallel-group design RCTs in adults with chronic kidney disease on dialysis therapy or with a kidney transplant published in MEDLINE in 2007 and 2008.

Outcomes & measurements

(1) How often was there loss to analysis, defined as not all randomly assigned participants included in primary outcome analysis? (2) Ho

SUBMITTER: Deo A 

PROVIDER: S-EPMC11661496 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature