Urine analysis in monoclonal gammopathies at diagnosis: settling cut-off values.

ABSTRACT:

Objectives

Laboratory testing has an extensive role in the diagnosis of monoclonal gammopathies. Since the last updates of the International Myeloma Working Group (IMWG) guidelines for the diagnosis of monoclonal gammopathies, debate has arisen as to whether urine analysis remains relevant for the diagnosis of these entities.

Methods

We carried out a retrospective study with data from 132 patients with a newly diagnosed serum M-protein. Patients were divided into two groups depending on the presence of M-protein in urine and different variables were recorded and statistically compared between groups.

Results

The aim of the study was to find a serum M-protein cut-off value under which urine analysis could be avoided in the first laboratory diagnosis. The results show t

SUBMITTER: Vidal-Pla M 

PROVIDER: S-EPMC11661531 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature