Proline-Functionalized Magnetic Nanoparticles as Highly Performing Asymmetric Catalysts.

ABSTRACT: Amino acids have a crucial role in the field of asymmetric organocatalysis for the production of chiral compounds with high added value and specific biological activity. In particular, proline offers high activity and stereoselectivity for catalyzing aldol reactions in organic solvents. However, proline-based catalysts often lack water-solubility, accessibility, catalytic performance, or recovery in aqueous media. This work reports the design of proline-functionalized poly(methyl methacrylate) (PMMA) nanoparticles with a magnetic core that offer high availability of chiral units in water and high recyclability. A proline-based copolymerizable surfactant is designed and integrated onto the surface of PMMA nanoparticles through a miniemulsion polymerization process without using additional s

SUBMITTER: Alvarez-Bermudez O 

PROVIDER: S-EPMC11661664 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature