Mechanical Power Is Associated With Mortality in Pressure-Controlled Ventilated Patients: A Dutch, Single-Center Cohort Study.

ABSTRACT:

Importance

Mechanical power (MP) could serve as a valuable parameter in clinical practice to estimate the likelihood of adverse outcomes. However, the safety thresholds for MP in mechanical ventilation remain underexplored and contentious.

Objectives

This study aims to investigate the association between MP and hospital mortality across varying degrees of lung disease severity, classified by Pao2/Fio2 ratios.

Design, setting, and participants

This is a retrospective cohort study using automatically extracted data. Patients admitted to the ICU of a tertiary referral hospital in The Netherlands between 2018 and 2024 and ventilated in pressure-controlled mode were included.

Main outcomes and measures

Logistic regression, adjusted for age, sex, Acute Physiology and

SUBMITTER: Goedegebuur J 

PROVIDER: S-EPMC11661764 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature