Dorsolateral pontine lesions produce distinct ocular motor abnormalities with anatomical correlations.

ABSTRACT:

Background and purpose

The dorsolateral portion of the caudal pons contains the vestibular nucleus (VN) and inferior cerebellar peduncle (ICP) that play important roles in conveying and processing vestibular and ocular motor signals. This study aimed to characterize ocular motor abnormalities along with their anatomical correlations in dorsolateral pons (DLP) lesions.

Methods

We analyzed clinical features, and results of neuro-otological evaluations and neuroimaging of 18 patients with unilateral DLP lesions (17 with DLP infarction and 1 with cavernous malformation) from among 506 patients with pontine infarction in a stroke registry.

Results

Most of the patients (n = 16) presented with isolated acute vestibular syndrome (AVS). The involved structures within the DLP w

SUBMITTER: Kim HS 

PROVIDER: S-EPMC11662166 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature