Air pollution is linked to cognitive decline independent of hypersensitive C-reactive protein: insights from middle-aged and older Chinese.

ABSTRACT:

Background

Long-term air pollution exposure and inflammation are considered to be associated with cognitive decline. However, whether air pollution exposure related cognitive decline is dependent on inflammation remains uncertain.

Materials and methods

The present study collected data from China Health and Retirement Longitudinal Study (CHARLS) at baseline in 2011, with a follow up period in 2015. Concentration of air pollutants (particles with diameters ≤ 1.0 μm [PM₁], ≤ 2.5 μm [PM_2.5], ≤ 10 μm [PM₁₀], nitrogen dioxide [NO₂] and ozone [O₃]) were obtained from China High Air Pollutants (CHAP) dataset. Hypersensitive C-reactive protein (hs-CRP), a systemic inflammation marker, was measured in blood of subjects and cogniti

SUBMITTER: Huang L 

PROVIDER: S-EPMC11662488 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature