Clinical importance of patient-reported outcome measures in severe asthma: results from U-BIOPRED.

ABSTRACT:

Rationale

Knowledge about the clinical importance of patient-reported outcome measures (PROMs) in severe asthma is limited.

Objectives

To assess whether and to what extent asthma exacerbations affect changes in PROMS over time and asthma-specific PROMs can predict exacerbations in adult patients with severe asthma in usual care.

Methods

Data of 421 patients with severe asthma (62% female; mean age 51.9 ± 13.4 years; mean FEV₁ 67.5 ± 21.3%pred) from the U-BIOPRED cohort were analyzed. The included PROMs were: Asthma Control Questionnaire (ACQ5); Asthma Quality of Life Questionnaire (AQLQ); Hospital Anxiety and Depression scale (HADS); Epworth Sleepiness Scale (ESS); Medication Adherence Report Scale (MARS); Sino-Nasal Outcomes Test (SNOT20). Participants wer

SUBMITTER: Meys R 

PROVIDER: S-EPMC11662558 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature