Comparing the clinical characteristics and outcomes of septic shock children with and without malignancies: a retrospective cohort study.

ABSTRACT:

Objective

There is an amelioration in mortality rates of septic shock patients with malignancies over time, but it remains uncertain in children. Therefore, the authors endeavored to compare the clinical characteristics, treatment needs, and outcomes of septic shock children with or without malignancies.

Methods

The authors retrospectively analyzed the data of children admitted to the PICU due to septic shock from January 2015 to December 2022 in a tertiary pediatric hospital. The main outcome was in-hospital mortality.

Results

A total of 508 patients were enrolled. The proportion of Gram-negative bacteria and fungal infections in children with malignancies was significantly higher than those without malignancies. Septic shock children with malignancies had a longer l

SUBMITTER: Huang H 

PROVIDER: S-EPMC11662747 | biostudies-literature | 2024 Nov-Dec

REPOSITORIES: biostudies-literature