Prognostic impact of lymphovascular invasion in node-negative gastric cancer: a retrospective cohort study.

ABSTRACT:

Background

Lymphovascular invasion (LVI) has been identified as a prognostic factor in various cancers, but its significance in node-negative gastric cancer remains unclear. Gastric cancer prognosis is notably affected by lymph node metastasis, with LVI potentially indicating metastatic spread.

Methods

A retrospective review was conducted on 5,699 patients who underwent curative radical gastrectomy for gastric cancer between 1989 and 2018. The median follow-up duration was 62 months (0-362 months). Overall, disease-specific, and disease-free survival were compared based on LVI status and stratified by T stage. Additionally, patients with stage IIA or T2N0 were further evaluated to clarify the clinical significance of LVI in the T2N0 group.

Results

The T2N0 LVI-positiv

SUBMITTER: Alangari AI 

PROVIDER: S-EPMC11662831 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature