Simultaneous quantitative screening of 53 phytochemicals from <i>Rheum tataricum</i> L. roots: a comparative study of supercritical CO₂, subcritical ethanol, and ultrasound-assisted extraction for enhanced antioxidant, antibacterial activities, and molecular docking study.

ABSTRACT: In this study, Rheum tataricum L. extracts were obtained using various green extraction techniques, including supercritical CO₂, subcritical ethanol, and ultrasound-assisted extraction, each performed under optimized parameters. The phytochemical content of the extracts was analyzed using the LC-MS/MS technique, quantifying 53 phytochemicals. Additionally, the in vitro antioxidant properties and antibacterial activities of the extracts were evaluated against Staphylococcus aureus and Enterococcus faecalis as gram-positive bacteria, and Escherichia coli and Pseudomonas aeruginosa as gram-negative bacteria. According to the results, the extracts were rich in catechin, epicatechin, cyranoside, and chlorogenic acid. Extracts obtained via ult

SUBMITTER: Amangeldinova M 

PROVIDER: S-EPMC11662978 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature