Hypoperfusion intensity ratio to differentiate between stroke etiologies in patients with a large vessel occlusion.

ABSTRACT:

Background

Collateral circulation plays a key role in acute ischemic stroke. We sought to determine the association between the arterial collateral status, estimated by the Hypoperfusion Intensity Ratio (HIR) on perfusion MRI, and stroke etiology in anterior circulation large vessel occlusion (LVO).

Methods

We retrospectively analyzed anterior circulation LVO acute stroke patients with a baseline perfusion MRI performed within 24 h from symptom onset. To avoid selection bias, patients were chosen from (1) the prospective registry of one comprehensive stroke center that included both thrombectomy-treated and untreated patients with systematic use of perfusion MRI and (2) one prospective thrombectomy study where perfusion MRI was acquired per protocol, but treatment decisions

SUBMITTER: Maruani A 

PROVIDER: S-EPMC11663280 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature