Assessing the comparative effects of interventions in COPD: a tutorial on network meta-analysis for clinicians.

ABSTRACT: To optimize patient outcomes, healthcare decisions should be based on the most up-to-date high-quality evidence. Randomized controlled trials (RCTs) are vital for demonstrating the efficacy of interventions; however, information on how an intervention compares to already available treatments and/or fits into treatment algorithms is sometimes limited. Although different therapeutic classes are available for the treatment of chronic obstructive pulmonary disease (COPD), assessing the relative efficacy of these treatments is challenging. Synthesizing evidence from multiple RCTs via meta-analysis can help provide a comprehensive assessment of all available evidence and a "global summary" of findings. Pairwise meta-analysis is a well-established method that can be used if two treatments have pr

SUBMITTER: Haeussler K 

PROVIDER: S-EPMC11663313 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature