Transient patterns of advanced brain ageing in female adolescents with anorexia nervosa.

ABSTRACT:

Background

Anorexia nervosa is a psychiatric disorder characterised by undernutrition, significantly low body weight and large, although possibly transient, reductions in brain structure. Advanced brain ageing tracks accelerated age-related changes in brain morphology that have been linked to psychopathology and adverse clinical outcomes.

Aim

The aim of the current case-control study was to characterise cross-sectional and longitudinal patterns of advanced brain age in acute anorexia nervosa and during the recovery process.

Method

Measures of grey- and white-matter-based brain age were obtained from T1-weighted magnetic resonance imaging scans of 129 acutely underweight female anorexia nervosa patients (of which 95 were assessed both at baseline and after approximatel

SUBMITTER: Stratton T 

PROVIDER: S-EPMC11663477 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature