Lung cancer screening by low-dose CT scan in France: final results of the DEP KP80 study after three rounds.

ABSTRACT:

Background

In prior randomised controlled trials, lung cancer screening using low-dose computed tomography (LDCT) has been shown to reduce lung cancer mortality and overall mortality. Despite these results, organised screening in France remains a challenge. This study assessed the feasibility and efficacy of lung cancer screening within a real-life context in a French administrative territory.

Methods

DEP KP80 was a single-arm prospective study. Participants aged between 55 and 74 years, smokers or former smokers of ≥30 pack-years, were recruited. An annual LDCT scan was scheduled and three rounds were performed. Subjects were selected by general practitioners or pulmonologists, who checked the inclusion criteria and prescribed the CT scan.

Findings

Between March 2016

SUBMITTER: Leleu O 

PROVIDER: S-EPMC11663785 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature