Causal Relationship Between the Abuse of Cholesterol-Lowering Medication, Blood Pressure Medication, Insulin, and Exogenous Hormones and Cerebral Infarction.

ABSTRACT:

Background

Cholesterol-lowering medications, blood pressure medication, insulin, and exogenous hormones (including hormone replacement therapy, oral contraceptives, and minipills) are commonly utilized in clinical practice. Recent studies indicate that the use of these medications may significantly influence the occurrence and progression of cerebral infarction. This study aims to investigate the relationship between these medications and cerebral infarction using Mendelian randomization (MR) analysis, with the goal of offering valuable insights for the clinical management of cerebral infarction.

Methods

To explore the correlation between cholesterol-lowering medication, blood pressure medication, insulin, exogenous hormones, and cerebral infarction, relevant single nucleoti

SUBMITTER: Liu J 

PROVIDER: S-EPMC11663836 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature