Association between psychiatric symptoms with multiple peripheral blood sample test: a 10-year retrospective study.

ABSTRACT:

Background

Psychiatric illness is thought to be a brain somatic crosstalk disorder. However, the existing phenomenology-based Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) diagnostic framework overlooks various dimensions other than symptoms. In this study, we investigated the associations between peripheral blood test indexes with various symptom levels of major depressive disorder (MDD), bipolar disorder (BD), and schizophrenia (SCZ) to explore the availability of peripheral blood test indexes.

Methods

We extracted cases diagnosed with MDD, BD, and SCZ at West China Hospital from 2009 to 2021, translated their main complaints into Research Domain Criteria (RDoC) symptom severity scores using nature language processing (NLP), and collected the

SUBMITTER: Qiu J 

PROVIDER: S-EPMC11663843 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature