Cognitive and cortical network alterations in pediatric temporal lobe space-occupying lesions: an fMRI study.

ABSTRACT:

Background

Temporal lobe mass lesions are the most common intracranial space-occupying lesions in children, among various brain lobes. The temporal lobe is critically involved in higher cognitive functions, and surgical interventions often risk causing damage to these functions. If necessary interventions and prehabilitation can be conducted preoperatively, it might be possible to achieve a larger extent of lesion resection with minimal cognitive impairment. However, research in this area has been relatively limited in the past. Our study aims to fill this gap.

Methods

We enrolled 15 children with temporal lobe mass lesions and 15 age- and gender-matched healthy children as controls. All participants underwent cognitive assessments and functional MRI scans. The cognitive tes

SUBMITTER: Hu B 

PROVIDER: S-EPMC11663916 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature