Association between white matter integrity and lower limb motor impairment after stroke: A systematic review: White matter integrity and lower limb motor impairment after stroke.

ABSTRACT:

Background

There is no clear consensus on the anatomical substrates required for recovery from lower limb (LL) impairment after stroke. Knowledge of biomarkers, such as white matter integrity (WMI), could fill this knowledge gap.

Objectives

To analyze the associations between WMI of the corticospinal tract (CST) and corticoreticulospinal pathway (CRP) and LL motor impairment after stroke, in terms of synergistic control and muscle strength. It also explores whether any associations depend on time post-stroke.

Methods

In April 2023, PubMed, Web of Science, and Scopus databases were systematically searched for studies associating WMI of the CST and CRP and LL motor impairment after stroke. Risk of bias was assessed using the Newcastle-Ottawa Quality Assessment Scales.

SUBMITTER: Loureiro-Chaves R 

PROVIDER: S-EPMC11663954 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature