Siesta behavior and genetics interact to influence obesity risk.

ABSTRACT:

Objective

In this cross-sectional study, we aim to investigate the interactions between obesity, siesta behavior, and the genetic propensity for siesta in a Mediterranean population, in whom siesta is deeply rooted.

Methods

We applied a previously generated Siesta-Polygenic Score (PGS) in the ONTIME study (n = 1278). Siesta and other Mediterranean lifestyle behaviors were characterized using questionnaires. We further determined obesity grade. Secondarily, we measured weight loss during treatment as well as long-term weight-loss maintenance. Logistic regression analyses were performed to address our aim.

Results

A total of 42.4% of the population usually took siesta. A significant genetic influence on siesta propensity was found, with a higher genetic predisposition l

SUBMITTER: Rodriguez-Martin M 

PROVIDER: S-EPMC11664305 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature