Evaluating the feasibility of modern external beam radiotherapy as an alternative approach to brachytherapy in endometrial cancer treatment: A systematic review.

ABSTRACT:

Purpose

This systematic review aimed to assess the feasibility, safety, and efficacy of using modern external beam radiotherapy (EBRT) techniques, such as intensity-modulated radiotherapy (IMRT), volumetric modulated arc therapy (VMAT), and stereotactic body radiotherapy (SBRT) as alternative approaches to brachytherapy (BRT) in adjuvant treatment of endometrial cancer (EC).

Material and methods

A systematic review was conducted following PRISMA guidelines. The research question was framed using the PICO method, focusing on patients with EC [P] and comparing modern EBRT techniques (IMRT, VMAT, SBRT) [I] vs. BRT [C], to evaluate their feasibility, safety, and effectiveness, particularly in terms of tumor local control (LC) [O]. Both planning and clinical outcomes, including a

SUBMITTER: Ferioli M 

PROVIDER: S-EPMC11664793 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature