Hypoglycemic agents and bone health; an umbrella systematic review of the clinical trials' meta-analysis studies.

ABSTRACT:

Background

No clear consensus exists regarding the safest anti-diabetic drugs with the least adverse events on bone health. This umbrella systematic review therefore aims to assess the published meta-analysis studies of randomized controlled trials (RCTs) conducted in this field.

Methods

All relevant meta-analysis studies of RCTs assessing the effects of anti-diabetic agents on bone health in patients with diabetes mellitus (DM) were collected in line with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). English articles published until 15 March 2023 were collected through the search of Cochrane Library, Scopus, ISI Web of Sciences, PubMed, and Embase using the terms "Diabetes mellitus", "anti-diabetic drugs", "Bone biomarker", "Bone fracture,

SUBMITTER: Khashayar P 

PROVIDER: S-EPMC11665059 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature