Protocol for a systematic review and meta-analysis of the combination of ezetimibe and statins for hyperlipidemia.

ABSTRACT:

Introduction

Hyperlipidemia is increasingly recognized as a significant global health issue, often associated with conditions such as hypertension, diabetes, and obesity. While statins are frequently prescribed to manage lipid levels, recent studies indicate that reliance solely on statin therapy may present certain disadvantages, including prolonged treatment durations, the potential for drug resistance, and various adverse effects. Research indicates that the combination of ezetimibe and statins demonstrates a favorable therapeutic effect in the management of hyperlipidemia. However, existing studies have not consistently confirmed these benefits, and there is no current meta-analysis available. As a result, we will perform a meta-analysis to assess the effectiveness and safety o

SUBMITTER: Yang T 

PROVIDER: S-EPMC11666007 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature