Electronically Controlled Dual-Wavelength Switchable SRS Fiber Amplifier in the NIR-II Region for Multispectral Photoacoustic Microscopy.

ABSTRACT: Photoacoustic microscopy (PAM) is a high-resolution and non-invasive imaging modality that provides optical absorption contrast. By employing dual- or multiple-wavelength excitation, PAM extends its capabilities to offer valuable spectroscopic information. To achieve efficient multispectral PAM imaging, an essential requirement is a light source characterized by a high repetition rate and switching rate, a ≈microjoule pulse energy, and a ≈nanosecond pulse duration. However, there exists a notable deficiency in suitable light sources, particularly in the near-infrared-II window. In this study, a custom-built all-fiber-based light source is reported that provides >3 μJ, 2 ns pulses with a repetition rate of 200 kHz. Digitally addressed semiconductor seed lasers, followed by stimulated Raman

SUBMITTER: Lee H 

PROVIDER: S-EPMC11666251 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature