Scent dogs identify SARS-CoV-2-infections in respiratory samples from experimentally infected ferrets and hamsters-a pilot study.

ABSTRACT: Rapid and sensitive diagnostic measures are a pre-requisite for the control of SARS-CoV-2 outbreaks. Dogs detect SARS-CoV-2-infected human individuals with high speed due to their extraordinary olfactory acuity. In the post-pandemic phase of SARS-CoV-2 it is difficult to obtain samples from infected humans for scent dog training. Established animal models for COVID-19 include hamsters and ferrets, which could overcome this shortcoming and have the advantage that samples are generated under controlled conditions. Respiratory samples from humans, hamsters and ferrets infected with SARS-CoV-2 and from ferrets infected with an H7-Influenza A virus were inactivated with β-propiolactone and presented via a device called "Detection Dog Training System" (DDTS). DDTS allows a fast, blinded,

SUBMITTER: Schulz C 

PROVIDER: S-EPMC11666280 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature