Internalized HIV stigma and viral suppression: examining the mediating and moderating roles of substance use and social support.

ABSTRACT:

Objective

The aim of this study was to examine the effects of internalized HIV stigma on viral nonsuppression via depressive symptoms, alcohol use, illicit drug use, and medication adherence and investigate whether social support moderates these effects.

Design

Longitudinal observational clinical cohort of patients in HIV care in the US.Methods: Data from the CFAR Network for Integrated Clinical Systems (2016-2019) were used to conduct structural equation models (SEM) to test the indirect effects of internalized HIV stigma on viral nonsuppression through depressive symptoms, illicit drug use, alcohol use, and medication adherence. Moderated mediation with an interaction between social support and internalized HIV stigma was examined.

Results

Among 9574 individuals inc

SUBMITTER: Crawford TN 

PROVIDER: S-EPMC11666411 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature