A generalized equation for predicting peak oxygen consumption during treadmill exercise testing: mitigating the bias from total body mass scaling.

ABSTRACT:

Background

Indexing peak oxygen uptake (VO₂peak) to total body mass can underestimate cardiorespiratory fitness (CRF) in women, older adults, and individuals with obesity. The primary objective of this multicenter study was to derive and validate a body size-independent scaling metric for VO₂peak. This metric was termed exercise body mass (EBM).

Method

In a cohort of apparently healthy individuals from the Fitness Registry and the Importance of Exercise National Database, we derived EBM using multivariable log-normal regression analysis. Subsequently, we developed a novel workload (WL) equation based on speed (Sp), fractional grade (fGr), and heart rate reserve (HRR). The generalized equation for VO₂peak can be expressed as VO₂peak

SUBMITTER: Santana EJ 

PROVIDER: S-EPMC11666446 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature