Association of serum iron with all-cause mortality and cardiovascular mortality in the cardiovascular patients: a retrospective cohort study based on the NHANES 1999-2018.

ABSTRACT:

Background

Cardiovascular disease (CVD) is one of the leading global causes of death, and serum iron (SI) levels may be associated with the mortality of CVD. However, there is still a knowledge gap regarding the relationship between SI and mortality in the CVD population.

Methods

An analysis was conducted utilizing data from the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2018. In our study, SI was used as the independent variable, and the mortality of the CVD patients was considered as the outcome. Kaplan-Meier curves, multivariable Cox proportional hazards model, and restricted cubic spline were employed to examine the association between SI and all-cause mortality and cardiovascular mortality in CVD patients. Subgroup analysis was also carried o

SUBMITTER: Lu J 

PROVIDER: S-EPMC11666567 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature