Reporting of somatic variants in clinical cancer care: recommendations of the Swiss Society of Molecular Pathology.

ABSTRACT: Somatic variant testing through next-generation sequencing (NGS) is well integrated into Swiss molecular pathology laboratories and has become a standard diagnostic method for numerous indications in cancer patient care. Currently, there is a wide variation in reporting practices within our country, and as patients move between different hospitals, it is increasingly necessary to standardize NGS reports to ease their reinterpretation. Additionally, as many different stakeholders-oncologists, hematologists, geneticists, pathologists, and patients-have access to the NGS report, it needs to contain comprehensive and detailed information in order to answer the questions of experts and avoid misinterpretation by non-experts. In 2017, the Swiss Institute of Bioinformatics conducted a survey to a

SUBMITTER: Christinat Y 

PROVIDER: S-EPMC11666653 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature