Association between trimethylamine N-oxide and prognosis of patients with myocardial infarction: a meta-analysis.

ABSTRACT:

Background

Trimethylamine N-oxide (TMAO) has been widely explored and considered as a biomarker for adverse cardiovascular events. However, the relationships between TMAO adverse cardiovascular events are inconsistent in patients. Therefore, this meta-analysis aimed to estimate association between TMAO levels and the prognosis of patients with myocardial infarction (MI).

Methods

We searched PubMed, EMBASE, the Cochrane Library, and Web of Science from inception to July 2, 2023, to retrieve all relevant clinical trials. Associations between TMAO levels, major adverse cardiovascular events (MACE), all-cause mortality, recurrent MI, stroke, etc., were systematically addressed. Outcomes included MACE, all-cause mortality, recurrent MI, rehospitalization caused by heart failure,

SUBMITTER: Li X 

PROVIDER: S-EPMC11666687 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature