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Continuous tremor monitoring in Parkinson's disease: A wristwatch-inspired triboelectric sensor approach.


ABSTRACT: Parkinson's disease (PD) prevalence is projected to reach 12 million by 2040. Wearable sensors offer a promising approach for comfortable, continuous tremor monitoring to optimize treatment strategies. Here, we present a wristwatch-like triboelectric sensor (WW-TES) inspired by automatic watches for unobtrusive PD tremor assessment. The WW-TES utilizes a free-standing design with a surface-modified polytetrafluoroethylene (PTFE) film and a stainless-steel rotor within a biocompatible polylactic acid (PLA) package. Electrode distance is optimized to maximize the output signal. We propose and discuss the WW-TES working mechanism. The final design is validated for activities of daily living (ADLs), with varying signal amplitudes corresponding to tremor severity levels ("normal" to "severe") b

SUBMITTER: Ukasi S 

PROVIDER: S-EPMC11667019 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature