Association between maternal systemic lupus erythematosus and infant infection: a population-based cohort study in Sweden.

ABSTRACT:

Objectives

The objectives of the study are to investigate infection risk in offspring born to women with systemic lupus erythematosus (SLE) compared with offspring born to women without SLE and examine the mediating role of preterm birth.

Design

This is a register-based cohort study.

Setting

Liveborn singletons born in Sweden, 2006-2021, were included in the study.

Participants

1248 infants born to mothers with SLE (≥2 International Classification of Diseases-coded visits in the National Patient Register (NPR) and Medical Birth Register, with ≥1 visit before pregnancy) and 34 886 infants born to women without SLE from the general population were included.

Primary and secondary outcome measures

The primary outcome was any visit for infection in the NPR or

SUBMITTER: Gernaat SAM 

PROVIDER: S-EPMC11667260 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature