Imaging, biomarkers, and vascular cognitive impairment in China: Rationale and design for the VICA study.

ABSTRACT:

Introduction

Vascular cognitive impairment (VCI) is highly heterogeneous, with unclear pathogenesis. Individuals with vascular risk factors (VRF), cerebral small vessel disease (CSVD), and stroke are all at risk of developing VCI. To address the growing challenges posed by VCI, the "Vascular, Imaging and Cognition Association of China" (VICA) was established.

Methods

VICA aims to recruit 10,000 participants, including 2000 with VRF, 3000 with CSVD, and 5000 stroke patients, to form a nationwide multicenter cohort. The study integrates clinical, neuroimaging, and multi-omics data to better understand VCI heterogeneity, improve disease prediction, and ensure timely diagnosis.

Results

VICA has screened 2045 eligible VRF participants from six communities in Wuhan, Shangha

SUBMITTER: Cui M 

PROVIDER: S-EPMC11667496 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature