LEAP! Rx: A randomized trial of a pragmatic approach to lifestyle medicine.

ABSTRACT:

Introduction

Clinicians lack the tools to incorporate physical activity into clinical care for Alzheimer's disease prevention. We tested a 52-week exercise and health education program (Lifestyle Empowerment for Alzheimer's Prevention [LEAP! Rx]) that integrates clinician referrals and community-based fitness resources.

Methods

We randomized 219 participants to the LEAP! Rx (ie, exercise and monthly brain health education) or a standard-of-care control group and tested the effects on cardiorespiratory fitness, insulin resistance, body composition, lipids, and cognitive performance.

Results

Physicians were able to connect their patients to a community lifestyle intervention. The intervention group increased in cardiorespiratory fitness at 12 and 52 weeks (p = 0.005). W

SUBMITTER: Watts A 

PROVIDER: S-EPMC11667554 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature