Early warning systems for identifying severe maternal outcomes: findings from the WHO global maternal sepsis study.

ABSTRACT:

Background

Infections and sepsis are leading causes of morbidity and mortality in women during pregnancy and the post-pregnancy period. Using data from the 2017 WHO Global Maternal Sepsis Study, we explored the use of early warning systems (EWS) in women at risk of sepsis-related severe maternal outcomes.

Methods

On April 27, 2023, we searched the literature for EWS in clinical use or research in obstetric populations. We calculated the proportion of women for whom each existing EWS identified them as at risk for developing severe maternal outcomes by infection severity (complications and severe maternal outcomes). Sensitivity, specificity, positive and negative likelihood ratios, diagnostic odds ratios, and J statistics were calculated to assess EWS performance. Machine lea

SUBMITTER: Chimwaza Y 

PROVIDER: S-EPMC11667637 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature